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輸血後鉄過剰症とフェロトーシス : 自著論文の紹介
https://doi.org/10.20608/00001043
https://doi.org/10.20608/00001043cdc7d884-39cc-49ed-9afd-2e78bbfa705e
名前 / ファイル | ライセンス | アクション |
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Bulletin12_12.pdf (559.2 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2019-03-31 | |||||
タイトル | ||||||
タイトル | 輸血後鉄過剰症とフェロトーシス : 自著論文の紹介 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Transfusion-iron overload and ferroptosis. Author's view. | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題 | 輸血後鉄過剰症 | |||||
キーワード | ||||||
主題 | マクロファージ | |||||
キーワード | ||||||
主題 | ヘミン | |||||
キーワード | ||||||
主題 | フェロトーシス | |||||
キーワード | ||||||
主題 | 鉄キレート剤 | |||||
キーワード | ||||||
主題 | transfusion iron overload | |||||
キーワード | ||||||
主題 | macrophages | |||||
キーワード | ||||||
主題 | haemin | |||||
キーワード | ||||||
主題 | ferroptosis | |||||
キーワード | ||||||
主題 | iron chelators | |||||
資源タイプ | ||||||
資源タイプ | departmental bulletin paper | |||||
ID登録 | ||||||
ID登録 | 10.20608/00001043 | |||||
ID登録タイプ | JaLC | |||||
著者 |
井本, しおん
× 井本, しおん× IMOTO, Shion |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 鉄過剰症は輸血依存患者の生命予後を悪化させる重要な問題である。輸血後鉄過剰症では、マクロファージに対するヘム鉄負荷が病態の中心となる。著者らは、ヘム鉄によって誘導されるマクロファージの細胞死が鉄依存性細胞死・フェロトーシスに合致することを見出し、Transfusion and Apheresis Scienceに論文報告した。論文の要点を、著者の見解を含めて紹介する。 | |||||
抄録(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Iron overload is a major issue for transfusion- dependent patients. Macrophages and heme iron play a central role in iron overload due to transfusion. We found that hemin-induced macrophage cell death is consistent with ferroptosis, an iron-dependent non-apoptotic cell death. Our results were recently published in "Transfusion and Apheresis Science". In the present report, I summarize the paper with my personal insight. | |||||
書誌情報 |
神戸常盤大学紀要 en : Bulletin of Kobe Tokiwa University 号 12, p. 73-75, 発行日 2019-03-31 |
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出版者 | ||||||
出版者 | 神戸常盤大学・神戸常盤大学短期大学部 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 18845487 | |||||
著者版フラグ | ||||||
出版タイプ | VoR |