@article{oai:kobe-tokiwa.repo.nii.ac.jp:00000465,
 author = {三浦, 真希子 and 竹浦, 久司 and 永尾, 暢夫 and MIURA, Makiko and TAKEURA, Hisashi and NAGAO, Nobuo},
 issue = {6},
 journal = {神戸常盤大学紀要, Bulletin of Kobe Tokiwa University},
 month = {Mar},
 note = {The Health and Labor Ministry of Japan recommends that antigen-negative red blood cells (RBCs) should be used when patients have clinically significant warm-reactive irregular antibodies. However, cold-reactive antibodies are not included in the guideline. Therefore, in this study we investigated low clinical significance of cold-reactive antibodies. We investigated the patients who had irregular antibodies between June 2006 and December 2010. A total of 6,030 blood samples from 3,559 patients were screened and 132 cases (2.19%) were positive for irregular antibodies. Ten warm-reactive antibodies in thirty-three cases and three cold-reactive in twenty-two cases (18 of anti-Lea including 3 of Coombs’ positive cases, 3 of anti-M, and 1 of anti-P1 antibody) were detected. Antigen-negative RBCs were secured for all the patients with warm-reactive antibodies, and compatibility tests were matched, except one case with a low-frequent antigen. Meanwhile, antigen-negative RBCs were not secured for the patients with cold-reactive antibodies, except Coombs’ positive cases. However, compatibility tests were matched, except two cases with dosage effect of anti-M antibody. No blood transfusion reaction was reported in cases with cold-reactive antibodies. Though antigen-negative RBCs were secured only for the patients with Coombs’ positive anti-Lea antibody, no hemolysis reactions with cold-reactive antibodies were reported. Cold-reactive antibodies were confirmed to be not clinically  significant., 3, KJ00009651360, 原著, Original Article},
 pages = {21--25},
 title = {不規則抗体の検出状況と低温性抗体の臨床的意義},
 year = {2013},
 yomi = {ミウラ, マキコ and タケウラ, ヒサシ and ナガオ, ノブオ}
}