{"created":"2023-06-20T13:09:49.829726+00:00","id":465,"links":{},"metadata":{"_buckets":{"deposit":"d4488320-0c6f-403f-bcc6-dcfc41a63e6a"},"_deposit":{"created_by":3,"id":"465","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"465"},"status":"published"},"_oai":{"id":"oai:kobe-tokiwa.repo.nii.ac.jp:00000465","sets":["6:18"]},"author_link":["5819","5817","5821","5818","5822","5820"],"item_3_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-03-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"25","bibliographicPageStart":"21","bibliographic_titles":[{"bibliographic_title":"神戸常盤大学紀要"},{"bibliographic_title":"Bulletin of Kobe Tokiwa University","bibliographic_titleLang":"en"}]}]},"item_3_description_11":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"The Health and Labor Ministry of Japan recommends that antigen-negative red blood cells (RBCs) should be used when patients have clinically significant warm-reactive irregular antibodies. However, cold-reactive antibodies are not included in the guideline. Therefore, in this study we investigated low clinical significance of cold-reactive antibodies. We investigated the patients who had irregular antibodies between June 2006 and December 2010. A total of 6,030 blood samples from 3,559 patients were screened and 132 cases (2.19%) were positive for irregular antibodies. Ten warm-reactive antibodies in thirty-three cases and three cold-reactive in twenty-two cases (18 of anti-Lea including 3 of Coombs’ positive cases, 3 of anti-M, and 1 of anti-P1 antibody) were detected. Antigen-negative RBCs were secured for all the patients with warm-reactive antibodies, and compatibility tests were matched, except one case with a low-frequent antigen. Meanwhile, antigen-negative RBCs were not secured for the patients with cold-reactive antibodies, except Coombs’ positive cases. However, compatibility tests were matched, except two cases with dosage effect of anti-M antibody. No blood transfusion reaction was reported in cases with cold-reactive antibodies. Though antigen-negative RBCs were secured only for the patients with Coombs’ positive anti-Lea antibody, no hemolysis reactions with cold-reactive antibodies were reported. Cold-reactive antibodies were confirmed to be not clinically  significant.","subitem_description_type":"Other"}]},"item_3_description_15":{"attribute_name":"表示順","attribute_value_mlt":[{"subitem_description":"3","subitem_description_type":"Other"}]},"item_3_description_16":{"attribute_name":"アクセション番号","attribute_value_mlt":[{"subitem_description":"KJ00009651360","subitem_description_type":"Other"}]},"item_3_description_8":{"attribute_name":"記事種別(日)","attribute_value_mlt":[{"subitem_description":"原著","subitem_description_type":"Other"}]},"item_3_description_9":{"attribute_name":"記事種別(英)","attribute_value_mlt":[{"subitem_description":"Original Article","subitem_description_type":"Other"}]},"item_3_identifier_14":{"attribute_name":"URL","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"http://bulletin.kobe-tokiwa.ac.jp/_src/622/038cb4929881q8eo89y905e8af38eq.pdf | http://bulletin.kobe-tokiwa.ac.jp/_src/622/038cb4929881q8eo89y905e8af38eq.pdf"}]},"item_3_source_id_1":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA12442114","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"21884781","subitem_source_identifier_type":"ISSN"}]},"item_3_text_6":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_value":"神戸常盤大学保健科学部医療検査学科"},{"subitem_text_value":"きつこう会多根総合病院中央検査部"},{"subitem_text_value":"神戸常盤大学保健科学部医療検査学科"}]},"item_3_title_3":{"attribute_name":"論文名よみ","attribute_value_mlt":[{"subitem_title":"フキソク コウタイ ノ ケンシュツ ジョウキョウ ト テイオンセイ コウタイ ノ リンショウ テキ イギ"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"三浦, 真希子"},{"creatorName":"ミウラ, マキコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"竹浦, 久司"},{"creatorName":"タケウラ, ヒサシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"永尾, 暢夫"},{"creatorName":"ナガオ, ノブオ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MIURA, Makiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TAKEURA, Hisashi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"NAGAO, Nobuo","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-09-08"}],"displaytype":"detail","filename":"Bulletin06_03.pdf","filesize":[{"value":"436.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Bulletin06_03.pdf","url":"https://kobe-tokiwa.repo.nii.ac.jp/record/465/files/Bulletin06_03.pdf"},"version_id":"e2dfbfce-43f3-4dcc-81c4-c4b9edc8957b"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"低音性抗体","subitem_subject_scheme":"Other"},{"subitem_subject":"不規則抗体","subitem_subject_scheme":"Other"},{"subitem_subject":"輸血副作用","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"不規則抗体の検出状況と低温性抗体の臨床的意義","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"不規則抗体の検出状況と低温性抗体の臨床的意義"},{"subitem_title":"Frequency of irregular antibodies and clinical significance of cold-reactive irregular antibodies","subitem_title_language":"en"}]},"item_type_id":"3","owner":"3","path":["18"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-09-08"},"publish_date":"2017-09-08","publish_status":"0","recid":"465","relation_version_is_last":true,"title":["不規則抗体の検出状況と低温性抗体の臨床的意義"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-20T13:23:39.839792+00:00"}